Abstract
Summary
Germ-free rats and mice tended to die sooner and within a narrower time span than conventional animals on exposure to 100% O2, suggesting that chronic respiratory conditions may increase resistance to O2 toxicity. Lung pathology of germ-free animals dying in O2 appeared much like that of chronic respiratory infection, indicating that inflammatory cell infiltration of the alveolar wall can occur in animals presumed free of disease.
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