Abstract
Summary
Hypophysectomized rats with multiple heterotopic pituitaries have nearly normal adrenal weight and significant, though subnormal, corticosterone secretion. Removal of the entire forebrain, but not decortication, in these animals reduced corticosterone secretion nearly to values found in hypophysectomized control animals. These results indicate that heterotopic pituitary ACTH secretion is dependent on some subcortical portion of the forebrain.
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