Abstract
Summary
Rabbits immunized with insoluble C. atrox venom-antivenom precipitate produced less precipitins and nearly as much neutralizing antibody as those injected with whole venom. The data show that venom neutralizing antibodies are precipitins and that the apparent non-relationship between precipitin titer and antitoxic value is the result of the polyvalency of venom-antivenom systems. The value of using insoluble antigen-antibody precipitates to isolate specific antigens, from a mixture, for immunization is pointed out.
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