Abstract
Summary
Transmural potentials across isolated segments of small intestine of the bullfrog, R. catesbeiana, were recorded. In sulphate saline the PD was higher than in chloride saline. Metabolic inhibitors depressed the PD. Actively transferred sugars and amino acids increased the PD when added to the mucosal fluid; this did not occur with the large intestine. Anoxia and dinitrophenol reduced the PD of the large intestine more than that of the small. The results indicate that bullfrog small intestine incubated in vitro is a stable and useful model for investigating the association between solute transfer, PD and energy sources.
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