Abstract
Summary
A group of normal and liver disease patients were given a standardized infusion of noradrenaline and release of FFA into the plasma measured. Patients with liver disease had no response to IV noradrenaline as regards a rise in peripheral FFA. Four possible explanations have been discussed. It appears likely that activation of hormone dependent tissue lipase is impaired in patients with liver disease, thus preventing the usual rise in FFA levels in response to exogenous norepinephrine.
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