Abstract
Summary
Twenty-five per cent of a group of Osborne-Mendel rats thymectomized within 24 hours of birth and injected with Moloney virus at 48 hours of age developed neoplasms, 8% malignant lymphoma, 17% reticulum cell sarcoma, while 95% of the intact group developed malignant lymphoma over the period of the study. All of the thymectomized rats tested, however, were producing virus. Similar deviations from normal were found in the serum protein patterns of both thymectomized and intact virus-inoculated rats.
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