Abstract
Summary
The guinea pig serum tumor inhibitory activity was effective for the ascites form of the Gardner lymphosarcoma. The active protein appears to be an enzyme L-asparaginase. Inhibition of the enzyme activity in normal pooled guinea pig serum in all cases caused a loss of the in vivo tumor inactivating capacity of the serum. Comparison of enzyme activity of fractionated serum correlates well with tumor destroying ability.
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