Abstract
Summary
Glutamic-oxalacetic transaminase (GOT), and glutamic-pyruvate transaminase (GPT), but not aldolase, were elevated in the serum of rats infected with Trypanosoma lewisi. Increased serum transaminase activity is believed to come from the host' tissues, which presumably are damaged by the parasite, as well as from the disintegrating parasite cells. All 3 enzymes were also present in lysed parasite cells. Here, transaminase activity was high, but aldolase was present in only minimal amounts. GPT was 9-fold more concentrated than GOT.
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