Abstract
Summary
The antagonism by a potent beta adrenergic blocking agent, MJ 1999, of the inhibition of dextran-induced rat paw edema by epinephrine was demonstrated. MJ 1999 did not antagonize the inhibition by either isoxsuprine or hydralazine as effectively as that by epinephrine. The importance of the beta receptor stimulating component in epinephrine inhibition was further seen by the lack of antagonism by phentolamine, an alpha blocking agent.
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