Abstract
Summary
A bio-assay procedure for highly potent anti-inflammatory steroids is described utilizing the changes in TCA-extractable liver glycogen content of either chick embryos at 12–16 days of incubation or of newly hatched chicks. The embryo assay is more sensitive than other commonly used bioassay procedures for determination of antiinflammatory steroids. Newly hatched chicks react to lesser extent, but seem to be suitable for rapid detection of small amounts of antiinflammatory steroids in crude biological samples (i.e., residues in animal tissues).
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