Abstract
Summary
Frozen and thawed Eperythrozoon coccoides in spleen homogenates was biologically active but aggregated. As a result, it was completely sedimented after 30 minutes at 5,000 × g, whereas from freshly prepared homogenates it was not completely sedimented even after one hour at 100,000 × g. In fresh infectious plasma, E. coccoides exhibited extreme particle heterogeneity as determined in a sucrose density gradient following centrifugation for 1 to 2 hours at 93,850 × g. Possible reasons for this behavior are discussed.
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