Abstract
Summary
After injection of heparin into corn oil-fed rats the level of plasma FFA was determined as a function of time. In the absence of metabolic alterations induced by fasting or by hormone administration or deletion, an elevation in plasma FFA was accompanied by a concomitant elevation in the concentration of blood ketone bodies. Control corn oil-fed rats injected with saline showed no such response. The results indicate that an increased level of plasma FFA per se can accelerate hepatic ketogenesis.
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