Abstract
Summary
The absorption of ricinoleic acid and its analogs has been studied in vivo. Corn oil, ricinoleic acid, triricinolein and methyl ricinoleate were administered by gastric intubation to rats with permanent thoracic duct cannulations. Corn oil administered to rats was readily emulsified, absorbed and transported to the lymph. Fifty per cent of the corn oil was absorbed in fasted rats. Maximum absorption of corn oil occurred after 8 hours, at which time 77% of the test fat was absorbed. Triricinolein and ricinoleic acid were completely absorbed after 27 hours, reaching maximum absorption within 24 hours after administration. The lymph lipids from rats fed the hydroxylated materials contained a low concentration of triglyceride and a higher concentration of mono- and diglycerides as well as free fatty acids when compared to that obtained from animals fed corn oil.
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