Abstract
Summary
Studies using C14-labelled guanylic acid demonstrated a rapid disappearance of these substances from the blood of intact and adrenalectomized rats. The application of tourniquets across the hind limbs of these animals produced a significantly decreased clearance of the label from the blood after the tourniquet was removed. It is suggested that changes in liver function together with increased release of intracellular nucleotides resulting from lymphatic involution or cellular damage may act to increase the blood nucleotide pool and cause an apparent slowing of the disappearance of the C14 from the blood.
Get full access to this article
View all access options for this article.