Abstract
Summary
Evidence is presented which indicates that there is present in the plasma of normal dogs a factor, possibly some type of plasma protein or a related substance, which inhibits in vitro biosynthesis of porphyrins from ALA. The amount of activity of this factor is decreased in the plasma of anemic phenylhydrazine-treated dogs. It is suggested that this plasma inhibitory factor may play a physiological role in regulating porphyrino-genesis.
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