Abstract
Summary
The urinary excretion of trypsin inhibitor produced by equal amounts of glucocorticoid hormone administered to man at 2 different periods of the day was studied. The hormonally induced increase in excretion was much larger during daytime than during the night. It is concluded that the response, in terms of urinary trypsin inhibitor excretion, to a given amount of glucocorticoid, (i.e., the sensitivity to the hormone) is much lower during the night than during the day.
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