Abstract
Summary
The non-protein sulfhydryl (NPSH) levels of liver stimulated to regenerate by partial hepatectomy increase to a maximum about 12 hours before the maximum mitosis occurs in the presence of a low protein-depletion diet which causes a decrease in NPSH in normal liver, and in the presence of nitrogen mustard which slows the process of mitosis. This pattern is similar to that found in regenerating liver not subject to these influences. Thus a rather direct influence of the mitotic process on sulfhydryl metabolism seems to exist.
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