Abstract
Summary
Determination of the ratios of sphingomyelin: lipid-galactose in brain and spinal cord of a group of E.A.E. rabbits and a group of normal rabbits showed remarkable similarity of the ratios within each of the groups of rabbits. Comparison of the values of the two groups with one another, however, showed that the sphingomyelin: lipid-galactose ratios of both brain and spinal cord from the E.A.E. rabbits were significantly lower than those from the normal ones. The metabolic-enzymatic cause of this change is subject of further investigation.
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