Abstract
Summary
The lipogenic activity of liver and kidney was compared. Kidney slices synthesize fatty acids at a considerably slower rate than do liver slices; an approximate estimate would place the rate of kidney slice lipogenesis at about 10-20% that of the liver slice. Kidney tissue appears to have a lower level of fatty acid synthesizing enzymes than liver but the difference in lipogenic rate of the intact cell is probably related to other factors as well. Kidney cytoplasmic particles suppress lipogenesis in kidney particle-free supernatant while liver cytoplasmic particles stimulate kidney particle-free supernatant lipogenesis, Thus, the presence of cytoplasmic particles in the kidney that inhibit rather than stimulate fatty acid synthesis probably is also related to difference in lipogenic activity between liver and kidney slices.
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