Effect of Triton Ingestion on Fat Absorption. ∗

Abstract

Summary

The effect of oral ingestion of Triton on fat absorption in rats was investigated by feeding either fat or Triton alone, or a combination of fat and Triton. Serum esterified fatty acid levels were elevated after the fat feeding but not in either case after Triton ingestion. An attempt to account for this decreased fat absorption was made by determining the effect on the lipolytic activity of pancreatic lipase of Triton, alone and in the presence of a bile acid. A marked inhibition of lipolysis occurred in both cases when Triton was present. The absence of any inhibitory effect of blood serum on lipase activity after the ingestion of massive amounts of Triton indicated that the Triton was not absorbed.