Abstract
Summary
Examination of the toxic filtrates from 9 strains of Cl. tetani by starch zone electrophoresis revealed a similar migration of the area of maximal neurotoxicity for the mouse. These observations are consistent with the view that a predominant neurotoxin is shared by all strains of this organism. The findings do not exclude the possibility of the existence of additional, perhaps minor, neurotoxins which may differ from strain to strain and which may account for the discrepancies reported in the behavior of toxic nitrates from different sources.
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