Abstract
Summary
Large doses of X-irradiation primarily to the head of the newborn rat 24 hours prior to infection with Coxsackie B1 virus resulted in an immediate increase in the titer of virus recovered from brain. Six days later a delayed rise was also detected in skeletal muscle harvested from a site distant from the point of maximum irradiation. In brain the increased viral yield was probably related to the simultaneous effects of ionizing radiation on both the head and the body. There is no satisfactory explanation for the delayed effect noted in muscle.
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