Abstract
Summary
3-Aminopropanol, like 2-amino-2-methylpropanol, increased the incidence of hemorrhagic kidneys and the level of liver fat of weanling male rats consuming a low-choline diet. Choline, dimethylethanolamine and monomethylethanolamine prevented the antilipotropic action of 3-aminopropanol. In the presence of 3AP betaine and methionine prevented the occurrence of kidney hemorrhages but only partially reduced the liver fat. Ethanolamine had little influence on the occurrence of hemorrhagic kidneys and only partially reduced the liver fat. Betaine and ethanolamine together in the diet were quite effective, whereas, methionine and ethanolamine together were only moderately effective. The inhibitory action of 3-aminopropanol was not as great as that of 2-amino-2-methyl-propanol.
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