Abstract
Summary
Rabbits acutely depleted of serum potassium or made chronically potassium deficient released more endogenous pyrogen following a constant pyrogenic stimulus than normokalemic controls. Increase of serum potassium to levels of 8.8 meq/1 did not alter the animals' ability to release endogenous pyrogen, and production of hypercalcemia also had no effect. These observations confirm the inhibitory effect of potassium on release of pyrogen from leukocytes in vitro.
Get full access to this article
View all access options for this article.