Abstract
Summary and conclusions
The “indirect” basophil degranulation technique was evaluated by replicate “blind” analyses of 8 sera. The results indicate that degranulation of basophils was a random phenomenon which was not influenced significantly by the presence or the absence of the antigen in the system or by the presumed presence or absence of antibody in the serum.
We would like to thank Dr. Max Samter and his colleagues in the Allergy Clinic, Research and Educational Hospitals, for collecting sera used in this study.
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