Abstract
Summary
The viruses of hog cholera and of transmissible gastroenteritis of swine were propagated in tissue cultures in an atmosphere of 95% oxygen and 5% carbon dioxide at a pressure of 10 1b per square inch. Under these conditions, cytopathic effects were observed in the tissue cultures 24 hours after virus inoculation. Conventional tissue cultures in rubber-stoppered tubes did not undergo cytopathic changes following inoculation with the 2 viruses. The cytopathic effects were neutralized by antiviral serum but were not affected by normal serum. Uninoculated tissue cultures were not affected by increased oxygen concentration.
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