Abstract
Summary
1. Preparations of the 4-amino, 4-acetamido and 4-benzamido derivatives of methyl-2-ethoxybenzoate and of 4-amino-2-ethylaminobenzoic acid are reported. 2. Anti-coccidial activity is demonstrated for 2-substituted PABAs, especially those containing 2-alkoxy, alkythio and alkylamino groups. 3. The most potent compounds are 4-amino-2-ethoxybenzoic acid and its ester and N-acyl derivatives.
The authors gratefully acknowledge the help of Mr. J. L. Ciminera in designing the statistical procedure used in the bio assay.
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