Abstract
Summary
The conventional patterns of radioactivity observed after filter paper electrophoresis of serum containing I-131-labeled thyroxine or triiodothyronine were altered by addition of nonionic surface-active agents in vitro. Triton X-100 or Tween 80 added to serum interfered with the binding of T4-I-131 or T3-I-131 by TEG and resulted in the migration of radio-hormones in the zone of the gamma globulins. The concentration of radioactivity found in the region of the gamma globulins depended on the quantity of non-ionic detergent which had been added to the serum.
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