Abstract
Summary
Homogenates of the neoplastic and adjacent non-malignant tissues from patients with adenocarcinoma of the colon were prepared and assayed spectrophotometrically for LD, MD, and enolase. Significant differences in enzyme activity were observed between the tumor homogenates and the homogenates of the uninvolved tissue. The activities of LD, MD, and enolase were significantly higher in the tumor preparations than in the preparations of adjacent mucosal tissue. These results are consistent with the hypothesis that the tumor proper is one of the sources of the elevated serum levels of the 3 enzymes.
Get full access to this article
View all access options for this article.