Abstract
Summary
1. Heparin in intravenous doses of 10 to 100 mg counteracted the immediate lethal effects of Russell's viper venom and tiger snake venom in rabbits, but did not prevent the deaths of the animals from the delayed toxic effects of the venom. 2. Heparin in the same intravenous doses did not interfere with the early death that occurs in endotoxin-treated rabbits given Russell's viper venom or tiger snake venom. 3. Heparin neither increased nor decreased the toxicity of moccasin venom in rabbits. 4. Finally, heparin did not affect the EIHS to Agkistrodon piscivorus venom when it was administered before endotoxin, shortly after endotoxin, or just before venom challenge.
The authors are greatly indebted to Miss Ann E. Gabrielsen for valuable criticism and advice in the preparation and editing of this work. They also appreciate the technical assistance of Messrs. Nils Rune Forsen, Thomas K. Norrie and Gene Monson.
Get full access to this article
View all access options for this article.