Stress and Susceptibility to Viral Infections. III. Antibody Response and Viral Retention During Avoidance Learning Stress. ∗

Abstract

Summary

Mice subjected to avoidance-learning stress for 2 weeks were inoculated intramuscularly with vesicular stomatitis virus. By measuring serum neutralizing antibodies, no differences in immune response between stressed and control mice were noted. Virus disappearance from the site of inoculation was significantly retarded in stressed mice. Analogous results were obtained with adrenalectomized mice.