Abstract
Summary
The distribution in pregnant mice of 14C-labelled thalidomide and glutethimide was investigated autoradiographically. After administration of 14C-thalidomide the radioactivity was found to penetrate through the placenta and to be distributed very evenly in both mother and fetuses. After administration of 14C-glutethimide a specific accumulation was seen in fat, brain, myocardium, blood vessel walls and mammary glands.
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