In vitro Uptake of Tritiated Thymidine by Erythrocytic Percursors Following Hemorrhage in the Dog. ∗

Abstract

Summary

Dogs were bled 40% of their blood volume (32 ml/kg). Thereafter, at intervals to 52 hours, the in vitro uptake of tritiated thymidine by erythrocytic precursors of the marrow did not differ from the controls as measured by percent labeling and grain counts in morphologically differentiated cells. Also, no alterations from control values were found with regard to morphological distribution, relative numbers of the marrow normoblasts, and mitotic index. The data suggest that the acute blood loss did not influence detectably the chosen parameters for the time intervals studied.