Abstract
Summary
Administration of 20% THAM citrate (pH 8.50) to dogs on a meat diet results in increase of the base content of the blood and in the production of an alkaline urine. Between 60 and 70% of the THAM administered is excreted daily in the urine indicating intestinal absorption. This treatment which was well tolerated over a 3-month period could have useful applications in clinical medicine.
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