Abstract
Summary
The effect of 4 acid polysaccharides on 2 variants of herpes virus was investigated by 3 different methods for measuring anti-viral activity. Dextran sulfate inhibited adsorption, plaque formation, and multicyclic viral growth in liquid medium. Heparin and agar polysaccharide inhibited adsorption and virus multiplication in liquid medium, while chondroitin sulfate was completely ineffective as an inhibitor. No diffference was noted in the behavior of the 2 variants with respect to their sensitivity toward the 4 sulfated polysaccharides.
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