Abstract
Summary
1. A method of fixation and composition of incubation media for staining acid ribonuclease in the peripheral leucocyte is described. 2. Localization of ribonuclease in the lysosome (specific granules of poly-morphonuclear leucocytes) and their possible heterogenic characters are discussed. 3. Since the technique described has reproducible and artifact-free results, it is hoped that it will facilitate investigation of ribonuclease in both blood and bone marrow cells in different pathological conditions.
We are grateful to Dr. E. Du Praw, Dept. of Zcology, Univ. of California, Davis, for helpful discussion and advice in preparing this paper.
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