Abstract
Summary
Rats with alloxan diabetes were made hydronephrotic and injected with E. coli intravenously. When 107 bacteria was injected, the incidence of pyelonephritis in hydronephrotic and contralateral kidneys was higher in diabetic than control animals. Alloxanized rats without hydronephrosis were also somewhat more susceptible to infection than controls. There was no relationship between degree of hyperglycemia and development of infection.
Get full access to this article
View all access options for this article.