Abstract
Summary
Groups of rats were injected with 150 units of bovine PTE over 28 hours. At the end of experiment they were injected intravenously with a standard dose of Ca45Cl2. The extent of the calcific changes was judged from von Kossa stained sections and from concentrations of Ca45/mg tissue. Striking enhancement of metastatic calcifications was observed in parathyroidectomized and in adrenalectomized rats. DOCA and hydrocortisone prevented the appearance of the calcific changes in adrenalectomized rats.
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