Abstract
Summary
A familial occurrence of β 2 macroglobulinaemia has been found in 4 instances. The antigenic structure of the macroglobulins in members of a given family has been investigated with antisera specific to the patients' macroglobulins. In one family, the serum of the asymptomatic mother contained 2 distinct kinds of macroglobulins and each of her 2 sons (affected with Waldenström disease) had one of them and not the other. In 2 other families, the antigenic structure of the macroglobulin was different in each of the 2 relatives.
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