Abstract
Summary
Pituitary explants on medium “199′”released an average of 0.05 IU prolactin daily. Pituitary-hypothalamus co-cultures released only an average of 0.025 IU/d. Other brain parts in co-culture failed to depress prolactin release, nor did hypothalami of perphenazine-primed rats or hypothalami to which perphenazine was added in vitro. The method described is a valuable tool for appraisal of prolactin releasing or inhibiting agents.
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