Liver Nonprotein Sulfhydryl in Vitamin B 6 -Deficient Rats

Abstract

Summary

Liver nonprotein sulfhydryl (NPSH) values in nonfasted Vit. B₆-deficient rats fed a 20% casein diet were similar to the values in nonfasted pair-fed or ad libitum-fed controls. Liver NPSH was altered by fasting, but the effect of fasting varied with the age of the animal. Fasting reduced liver NPSH by only 28% in rats depleted of Vit. B₆ for 19–26 days after weaning, but caused a 63% reduction in the liver NPSH in the controls of the same age. This effect produced an apparent “increase”in the liver NPSH in the fasted deficient rats. In rats fed the experimental diet for approximately 70 days, fasting caused similar decreases in NPSH in both the deficient and the control groups.