Abstract
Summary
Corticosterone in plasma and urine was determined by spectrofluorometry in sulfuric acid and by direct spectrophotometry in ethanol. Plasma levels and urinary excretion of corticosterone were elevated in rats with subcutaneous lymphomas. The high plasma concentration of corticosterone in these rats may help to explain the reduction in splenic, thymic and lymphoid tissue of lymphoma-bearing rats and certain interactions of exogenous steroids, quantity of lymphoma tissue and tumor-necrotizing effect of K. pneumoniae polysaccharide.
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