Abstract
Summary
The activities of 2 mitochondrial respiratory enzymes were determined in the liver of normal rats and of rats treated with cortisone and/or anabolic steroid Methandrostenolone. The activities of malic dehydrogenase and DPN-cytochrome-c-reductase were decreased in cortisone treated rats. This depression was reversible and interruption of treatment resulted in normalization of activities of both enzymes. Simultaneous treatment of rats by cortisone and the anabolizer did not, however, prevent this depression. The activities of both enzymes were increased in rats treated with Methandrostenolone alone.
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