Abstract
Summary
THAM, 0.3 M, protected mice from the CNS symptoms of oxygen toxicity at 4 atm. This was shown by the prolonged time required before onset of seizure activity. The same concentration of THAM did not protect at 6 atm. Addition of low concentrations of KCl and NaCl appeared to reverse this protection. A mixture of THAM, 0.6 M, and 0.15 M KCl is lethal to mice.
Get full access to this article
View all access options for this article.