Abstract
Summary
Immature rats were fed graded levels of DBH in conjunction with either a highly purified or natural food stock ration. A significant difference in response to DBH administration was observed between rats fed the 2 diets. On the stock ration DBH when fed at levels of 0.1%, 0.15% or 0.2% of the diet had little, if any, adverse effect on weight increment and none on gross appearance. When fed at comparable levels in the purified ration, however, DBH caused a significant retardation in growth, an unhealthy appearance, varying degrees of alopecia, and at the 0.2% level, death. The protective factor or factors in the stock ration was distinct from any of the known nutrients.
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