Abstract
Summary
1. The effect of single doses of arsenate, bilirubin, dinitrophenol and oligomycin on synthesis of mitochondria phospholipids of the liver of rats was studied. 2. A statistically significant decrease occurred in synthesis of phosphatidyl inositol, sphingomyelin, lecithin, phosphatidyl serine and phosphatidyl ethanolamine of liver mitochondria following administration of dinitrophenol. 3. Administration of arsenate, oligomycin and bilirubin inhibited statistically the incorporation of the isotope into all the phospholipid fractions of liver mitochondria except sphingomyelin and phosphatidyl inositol. However, oligomycin inhibited incorporation of the isotope into the sphingomyelin fraction and arsenate inhibited the phosphatidyl inositol fraction.
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