Abstract
Summary
Cyanide-adapted Tetrahymena pyriformis show considerable alteration in glucose, acetate and amino acid metabolism. Total lipid metabolism is not changed. Although adapted cells remove more amino acid from the culture medium during growth, this appears more due to accumulation and/or conversion to other materials than to increased oxidation. Methionine, proline, serine and valine oxidative activities are especially lowered upon adaptation, as is glucose oxidation. Adapted cells show marked increase in oxidation of phenylalanine, isoleucine and threonine, as well as acetate.
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