Effect of Stimulation of Autonomic Outflow to Urinary Bladder of Rhesus Monkey. ∗

Abstract

Discussion and conclusions

These data indicate that stimulation of the hypogastric nerves, unlike those previously recorded in the cat and dog, and by others in the monkey (1,2), were largely ineffective. The usual response was a weak contraction which appeared after 15 to 20 seconds of stimulation and was always difficult to distinguish from normal, spontaneous rhythm of the bladder. Often there was no response to sympathetic nerve stimulation. On the other hand, excitation of pelvic nerves evoked contractions similar in almost all respects to those obtained in the cat and dog and by others in the monkey (1,2).

Altering the frequency of the current, changing intravesical pressure, or section of the nerves and stimulation of their peripheral cut ends, had no effect upon the response following either hypogastric or pelvic nerve stimulation. Bladder responses in both males and females apparently were the same.