Abstract
Summary
The effects of dimethyl sulfoxide (DMS) and glycerol on K and Na content of freeze-thawed rabbit heart muscle have been determined. Both right atrial and left ventricular tissue were found to lose K and gain Na after freeze-thawing compared to freshly dissected tissue. The presence of 10% DMS or 15% glycerol during freeze-thawing did not prevent this loss of K or gain of Na. Glycerol was also found to produce a loss of K in ventricular tissue even in the absence of freeze-thawing.
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