Abstract
Summary
1. A method is described for measuring “cholesterol uptake” of serum incubated with solid cholesterol. 2. The method has been used to measure cholesterol uptake of serum from normal young men and from older men hospitalized with cardiovascular disease. 3. All sera examined were found to dissolve additional cholesterol. 4. Cholesterol uptake by serum from the hospitalized group was equal to or greater than uptake by serum from the normal group. 5. The data indicate that the capacity of serum lipoproteins to bind cholesterol is not fully saturated in either the normal young men or in the patients with atherosclerosis.
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